diff -uNr Pillow-9.2.0/setup.py Pillow-9.2.0.mod/setup.py
--- Pillow-9.2.0/setup.py	2022-07-01 22:19:51.000000000 +0900
+++ Pillow-9.2.0.mod/setup.py	2022-10-13 23:03:54.800557858 +0900
@@ -497,8 +497,8 @@
                 for d in os.environ[k].split(os.path.pathsep):
                     _add_directory(library_dirs, d)
 
-        _add_directory(library_dirs, os.path.join(sys.prefix, "lib"))
-        _add_directory(include_dirs, os.path.join(sys.prefix, "include"))
+        _add_directory(library_dirs, os.path.join("%TERMUX_PREFIX%", "lib"))
+        _add_directory(include_dirs, os.path.join("%TERMUX_PREFIX%", "include"))
 
         #
         # add platform directories
@@ -567,7 +567,7 @@
             or sys.platform.startswith("gnu")
             or sys.platform.startswith("freebsd")
         ):
-            for dirname in _find_library_dirs_ldconfig():
+            for dirname in []:
                 _add_directory(library_dirs, dirname)
             if sys.platform.startswith("linux") and os.environ.get(
                 "ANDROID_ROOT", None
@@ -595,7 +595,7 @@
         # FIXME: check /opt/stuff directories here?
 
         # standard locations
-        if not self.disable_platform_guessing:
+        if False:
             _add_directory(library_dirs, "/usr/local/lib")
             _add_directory(include_dirs, "/usr/local/include")