--- a/src/pip/_internal/utils/appdirs.py
+++ b/src/pip/_internal/utils/appdirs.py
@@ -49,4 +49,4 @@ def site_config_dirs(appname: str) -> List[str]:
         return [dirval]
 
     # Unix-y system. Look in /etc as well.
-    return dirval.split(os.pathsep) + ["/etc"]
+    return dirval.split(os.pathsep) + ["@TERMUX_PREFIX@/etc"]
--- a/src/pip/_vendor/platformdirs/unix.py
+++ b/src/pip/_vendor/platformdirs/unix.py
@@ -79,7 +79,7 @@ class Unix(PlatformDirsABC):  # noqa: PLR0904
     def _site_config_dirs(self) -> list[str]:
         path = os.environ.get("XDG_CONFIG_DIRS", "")
         if not path.strip():
-            path = "/etc/xdg"
+            path = "@TERMUX_PREFIX@/etc/xdg"
         return [self._append_app_name_and_version(p) for p in path.split(os.pathsep)]
 
     @property